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The characterisation of protein binding in paediatric extracorporeal membrane oxygenation (ECMO) circuits

ABSTRACT: The present study aims to characterise proteins bound to circuits collected from children on extracorporeal membrane oxygenation (ECMO). ECMO circuits were collected from 6 patients. Quantification of concentrations for proteins bound to the ECMO circuit samples was performed using bicinchoninic acid (BCA) protein assay, whilst characterisation of the bound proteome was performed using Data-independent acquisition Mass Spectrometry (DIA-MS). Reactome Over-representation Pathway Analyses tool was used to identify functional pathways corresponding to the common proteins bound to circuits across all patients.

INSTRUMENT(S): timsTOF Pro

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

SUBMITTER: Laura Dagley

LAB HEAD: Prof Vera Ignjatovic

PROVIDER: PXD045889 | Pride | 2024-10-07

REPOSITORIES: Pride

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			Action	DRS
	DIANN_libfree_161221.zip	Other
	P4117_12_1_1_7083.d.zip	Other
	P4117_18_1_1_7079.d.zip	Other
	P4117_23_1_1_7071.d.zip	Other
	P4117_24_1_1_7080.d.zip	Other

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