Ubiquitinome of G401 SMARCB1-deficient rhabdoid tumor cells
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ABSTRACT: In this study, DCAF5, a substrate receptor that has been shown to modulate the levels of SWI/SNF subunits, which are components of a chromatin remodeling complex. Here we preformed ubiquitinome proteomics to discover the underlying response of DCAF5 loss on ubiquitylation of SWI/SNF subunits. Furthermore, we determine what sites on SWI/SNF components decrease in ubiquitylation upon DCAF5 loss.
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Zhiping Wu
LAB HEAD: Junmin Peng
PROVIDER: PXD046463 | Pride | 2024-03-25
REPOSITORIES: Pride
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