Ubiquitinome of G401 SMARCB1-deficient rhabdoid tumor cells

ABSTRACT: In this study, DCAF5, a substrate receptor that has been shown to modulate the levels of SWI/SNF subunits, which are components of a chromatin remodeling complex. Here we preformed ubiquitinome proteomics to discover the underlying response of DCAF5 loss on ubiquitylation of SWI/SNF subunits. Furthermore, we determine what sites on SWI/SNF components decrease in ubiquitylation upon DCAF5 loss.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Zhiping Wu  

LAB HEAD: Junmin Peng

PROVIDER: PXD046463 | Pride | 2024-03-25

REPOSITORIES: Pride