Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Susanne Bandau
LAB HEAD: Constance Alabert
PROVIDER: PXD046546 | Pride | 2024-02-14
REPOSITORIES: Pride
Bandau Susanne S Alvarez Vanesa V Jiang Hao H Graff Sarah S Sundaramoorthy Ramasubramanian R Gierlinski Marek M Toman Matt M Owen-Hughes Tom T Sidoli Simone S Lamond Angus A Alabert Constance C
EMBO reports 20240212 3
Understanding how chromatin organisation is duplicated on the two daughter strands is a central question in epigenetics. In mammals, following the passage of the replisome, nucleosomes lose their defined positioning and transcription contributes to their re-organisation. However, whether transcription plays a greater role in the organization of chromatin following DNA replication remains unclear. Here we analysed protein re-association with newly replicated DNA upon inhibition of transcription u ...[more]