Characterize proteome-wide changes in protein abundance and ubiquitination during glucose starvation in wild-type and HOIL-1mut AC16 cardiomyocytesCharacterize proteome-wide changes in protein abundance and ubiquitination during glucose starvation in wild-type and HOIL-1mut AC16 cardiomyocytes

ABSTRACT: The cells expressing a truncated form of the E3 ubiquitin ligase HOIL-1 are hypersensitive to lethal metabolic stress. We hypothesize that alterations in ubiquitination or abundance of key substrates constitutes a mechanistic underpinning of this phenotype.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Zhiping Wu  

LAB HEAD: Junmin Peng

PROVIDER: PXD046661 | Pride | 2026-03-13

REPOSITORIES: Pride