Proteome-wide analysis of S. cerevisiae controlled by the optogenetic cell cycle regulator bPAC (photo activatable adenylate cyclase from Beggiatoa)

ABSTRACT: The field of optogenetics offers a powerful toolbox to control cellular processes. We used the photo activatable adenylate cyclase from Beggiatoa to restrict cell-cycle progression under specific light conditions. In a label-free proteomics experiment we investigated the influence of cell-cycle restriction on the proteome, comparing cells grown under restrictive/permissive light conditions and wild-type cells.

INSTRUMENT(S):

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

TISSUE(S): Primary Cell

SUBMITTER: Christof Taxis  

LAB HEAD: Lars-Oliver Essen

PROVIDER: PXD046730 | Pride | 2026-04-24

REPOSITORIES: Pride