Proteome analysis of HepG2 WT and mitochondrial apolipoprotein MIC26 knockout cells under normo- and hyperglycemic conditions

ABSTRACT: Increased amounts of the mitochondrial apolipoprotein O /MIC26 were found in diabetic patients along with lipid accumulation in murine liver upon MIC26 expression. MIC26 is a MICOS complex constituent present in the mitochondrial inner membrane. Here, we employed a proteomics analysis approach in WT and MIC26 knockout HepG2 cellular models in normoglycemic and hyperglycemic conditions.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hepatocyte, Liver

SUBMITTER: Anja Stefanski  

LAB HEAD: Kai Stühler

PROVIDER: PXD047246 | Pride | 2024-09-13

REPOSITORIES: pride