Specialized replication mechanisms maintain genome stability at human centromeres

ABSTRACT: Reveal a specific set of proteins important to maintain centromere integrity, through quantitative PICh (Proteomics of Isolated Chromatin). Centromeric chromatin was pulled down through RNA probes annealing specifically to a 300bp-long conserved centromeric sequence.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

SUBMITTER: Frank Stein  

LAB HEAD: Daniele Fachinetti

PROVIDER: PXD047847 | Pride | 2024-02-14

REPOSITORIES: Pride