Exploring roles of the chitinase ChiC in modulating Pseudomonas aeruginosa virulence phenotypes

ABSTRACT: Chitinases are ubiquitous enzymes involved in biomass degradation and chitin turnover in nature. Pseudomonas aeruginosa (PA), an opportunistic human pathogen, expresses ChiC, a secreted glycoside hydrolase 18 (GH18) family chitinase. Despite speculation about ChiC's role in PA disease pathogenesis, there is scant evidence supporting this hypothesis. Since PA cannot catabolize chitin, we investigated the potential function(s) of ChiC in PA pathophysiology

INSTRUMENT(S):

ORGANISM(S): Pseudomonas Aeruginosa Pao1 Bacteria

SUBMITTER: Per Kristian Edvardsen  

LAB HEAD: Gustav Vaaje-Kolstad

PROVIDER: PXD048596 | Pride | 2024-04-30

REPOSITORIES: Pride