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Egr1 is a master regulator of regenerative senescence and cardiac repair

ABSTRACT: The protein signatures in two mouse models of cardiac regeneration reveal enriched senescence gene sets, and Egr1 is the key regulator for regenerative senescence.Cathepsin S, a regenerative senescence-secreted component, promotes the degradation of the extracellular matrix, contributing to cardiac repair.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Heart

SUBMITTER: Yishai Levin

LAB HEAD: Eldad Tzahor

PROVIDER: PXD048877 | Pride | 2024-05-07

REPOSITORIES: Pride

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