Proteomics

Dataset Information

Sex-Dependent effects of Sortilin antisense oligonucleotide on Ldlr-/- mice

ABSTRACT: We evaluated the therapeutic potential of silencing sortilin expression in vivo using antisense oligonucleotide (ASO-Sort1) to reduce atherosclerosis and associated calcification. Male and female Ldl (low-density lipoprotein) receptor deficient mice were fed a high-fat diet and treated with ASO-Sort1 for 15 weeks.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Aortic Arch

SUBMITTER: Adrien Lupieri  

LAB HEAD: Dr Elena

PROVIDER: PXD048883 | Pride | 2026-06-15

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
12_DBG_ASO_SORT1_Mice_AorticArch.mzML Mzml
12_DBG_ASO_SORT1_Mice_AorticArch.mzid.gz Mzid
12_DBG_ASO_SORT1_Mice_AorticArch.pdResult Other
12_DBG_F_AoArch_Control_F1107dTopS_CID-IT_90min.raw Raw
12_DBG_F_AoArch_Control_F1207dTopS_CID-IT_90min.raw Raw
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