Dataset Information

Bacillus subtilis, sediment, diaPASEF

ABSTRACT: The collected bacteria were centrifuged to remove the fermentation liquid and then 4D-lable free proteomic detection was performed

INSTRUMENT(S):

ORGANISM(S): Bacillus Subtilis Subsp. Subtilis Bacteria

TISSUE(S): Cell Suspension Culture

SUBMITTER: Caiyun Wu

LAB HEAD: Wu Cai yun

PROVIDER: PXD049242 | Pride | 2025-05-06

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	Database_search_result.rar	Other
	checksum.txt	Txt
	original_data.rar	Other

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Publications

Analysis of glutamate-dependent mechanism and optimization of fermentation conditions for poly-gamma-glutamic acid production by Bacillus subtilis SCP017-03.

Wu Caiyun C Gou Yutao Y Jing Shuai S Li Wei W Ge Fanglan F Li Jiao J Ren Yao Y

PloS one 20250130 1

Poly-gamma-glutamic acid (γ-PGA) is mainly synthesized by glutamate-dependent strains in the manufacturing industry. Therefore, understanding glutamate-dependent mechanisms is imperative. In this study, we first systematically analyzed the response of Bacillus subtilis SCP017-03 to glutamate addition by comparing transcriptomics and proteomics. The introduction of glutamate substantially altered gene expression within the central metabolic pathway of cellular carbon. Most genes in the pentose ph ...[more]

PMID: 39883687

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