Helical superstructures between amyloid and collagen VI in heart derived fibrils from a patient with Light Chain Amyloidosis

ABSTRACT: We investigated the N- and C-terminome of the LCs proteoforms in fibrils extracted from the hearts of a patient affected by AL amyloidosis, using a proteomic approach based on N- and C-terminal residues derivatization, followed by mapping of fragmentation sites on the structures of fibrillar LCs

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Heart

DISEASE(S): Immunoglobulin Light Chain Amyloidosis

SUBMITTER: Giulia Mazzini  

LAB HEAD: Giovanni Palladini

PROVIDER: PXD049301 | Pride | 2024-07-02

REPOSITORIES: Pride