Dataset Information
Mast cells modulate macrophage through release of Csf1
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Secretion, Cell Culture, Macrophage Colony-stimulating Factor 1 Receptor (human), Mast Cell Activation Involved In Immune Response
SUBMITTER: 
Piero Giansanti
LAB HEAD: Piero Giansanti
PROVIDER: PXD050282 | Pride | 2025-06-23
REPOSITORIES: Pride
Dataset's files
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Publications
Mast cells modulate macrophage biology through release of pre-stored CSF1.
The Journal of allergy and clinical immunology 20250604
<h4>Background</h4>Mast cells are tissue-resident immune cells present in connective tissues throughout the body. They exert diverse functions in immunity by rapidly releasing a plethora of preformed mediators, including proteoglycans, cytokines, and proteases, which are stored in cytoplasmic granules.<h4>Objective</h4>Our aim was to systematically and globally identify mast cell-released protein mediators and elucidate their functions.<h4>Methods</h4>We analysed the secretomes of antigen-activa ...[more]