Proteomics

Dataset Information

0

Untargeted virus identification via LC-MS/MS based proteotyping


ABSTRACT: A novel tandem mass spectrometry proteotyping-based method that offers an untargeted approach for the identification of pathogenic viruses and other components, eliminating the need for a priori knowledge of the sample composition, has been developped.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Sindbis Virus Homo Sapiens (human) Rio Negro Virus Vaccinia Virus Pixuna Virus

SUBMITTER: Jean ARMENGAUD  

LAB HEAD: Jean Armengaud

PROVIDER: PXD050318 | Pride | 2025-05-06

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
E03264_Virus_5.mgf Mgf
E03264_Virus_5.raw Raw
E21696_Saliva_2_Vaccine5E6.mgf Mgf
E21696_Saliva_2_Vaccine5E6.raw Raw
E21698_Saliva_8_Vaccine5E6.mgf Mgf
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Publications

Universal Identification of Pathogenic Viruses by Liquid Chromatography Coupled with Tandem Mass Spectrometry Proteotyping.

Lozano Clément C   Pible Olivier O   Eschlimann Marine M   Giraud Mathieu M   Debroas Stéphanie S   Gaillard Jean-Charles JC   Bellanger Laurent L   Taysse Laurent L   Armengaud Jean J  

Molecular & cellular proteomics : MCP 20240730 10


Accurate and rapid identification of viruses is crucial for an effective medical diagnosis when dealing with infections. Conventional methods, including DNA amplification techniques or lateral-flow assays, are constrained to a specific set of targets to search for. In this study, we introduce a novel tandem mass spectrometry proteotyping-based method that offers a universal approach for the identification of pathogenic viruses and other components, eliminating the need for a priori knowledge of  ...[more]

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