EGFR-TKI-down-regulated proteins in HCC827 cells

ABSTRACT: EGFR mediates stabilities of a wide spectrum of proteins. Treatment of the cells with EGFR tyrosine kinase inhibitors (EGFR-TKIs) leads to degradation of these proteins. To define the proteins and corresponding pathways of EGFR-stabilized proteins, we use mass spectrum to quantify the protein levels in the untreated control HCC827 cells and the cells treated with erlotinib or gefitinib.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Li Zheng  

LAB HEAD: Binghui Shen

PROVIDER: PXD050420 | Pride | 2025-05-13

REPOSITORIES: Pride