Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α

ABSTRACT: We engineered a cell-tethered version of the extracellular kinase CK2α, demonstrated it was active on cells under tumor-relevant conditions, and profiled its substrate scope using a chemoproteomic workflow.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Breast Cancer

SUBMITTER: Corleone Delaveris  

LAB HEAD: James A Wells

PROVIDER: PXD050801 | Pride | 2024-07-16

REPOSITORIES: Pride