Investigating the impact of GalNAc-T2 overexpression on proteomics and glycoproteomics in lung cell

ABSTRACT: GalNAc-T2 was identified as a novel antiviral factor that promotes viral clearance and contributes to reduced disease severity.This project aimed to investigate the impact of GalNAc-T2 overexpression on proteomics and glycoproteomics in lung cell. We employ SILAC labeling, lectin-based affinity enrichment, and LC-ETD MS/MS to characterize the regulated proteins and glycosylation sites resulting from GalNAc-T2 overexpression.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Cell Culture

SUBMITTER: Yuqi He  

LAB HEAD: Yang Mao

PROVIDER: PXD051101 | Pride | 2026-01-12

REPOSITORIES: Pride