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Unraveling developmental gene regulation in holometabolous insects through comparative transcriptomics and proteomics

ABSTRACT: We here provide a comprehensive paired proteome and transcriptome data set including major stages (egg, larva, pupa and adult) across the whole developmental life cycle of the silkworm Bombyx mori. Our data constitutes a rich resource enabling comparative analysis of developmental regulatory dynamics. Analyzing this paired proteome and transcriptome data we revealed similarities and differences between both levels of gene expression in B. mori. We were also able to examine protein-transcript correlations and characterize stage-specific dynamics. Integrating similar publicly available data for D. melanogaster were also compared the two holometabolous insects at the level of the developmental proteome and transcriptome.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Bombyx Mori (silk Moth)

SUBMITTER: Maya Wilkens

LAB HEAD: Falk Butter

PROVIDER: PXD051369 | Pride | 2025-06-06

REPOSITORIES: Pride

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			Action	DRS
	20200708_SFB1_FBU_FB_bombyx_A5F_1.raw	Raw
	20200708_SFB1_FBU_FB_bombyx_A5F_2.raw	Raw
	20200708_SFB1_FBU_FB_bombyx_A5F_3.raw	Raw
	20200708_SFB1_FBU_FB_bombyx_A5F_4.raw	Raw
	20200708_SFB1_FBU_FB_bombyx_A5F_5.raw	Raw

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