Dataset Information

Proteomic Analysis of Intracellular Biomineralised Granules in the Deep-Sea Hydrothermal Vent Alvinellid Worm Paralvinella herssleri

ABSTRACT: In this project, we used liquid chromatography coupled with mass spectrometry to sequence the intracellular granules of the deep-sea Alvinellidae worm Paralvinella hessleri. These granules are composed of biomineralized orpiment.

INSTRUMENT(S):

ORGANISM(S): Paralvinella Hessleri

TISSUE(S): Organelle Membrane

SUBMITTER: Hao Wang

LAB HEAD: Hao Wang

PROVIDER: PXD051377 | Pride | 2025-09-08

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	Sample-1_skin1_2_Slot1-34_1_7401.d.zip	Other
	Sample-2_skin2_2_Slot2-2_1_8429.d.zip	Other
	Sample-3_skin3_2_Slot2-4_1_8433.d.zip	Other
	Sample1-search.zip	Other
	Sample2-search.zip	Other

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Publications

A deep-sea hydrothermal vent worm detoxifies arsenic and sulfur by intracellular biomineralization of orpiment (As2S3).

Wang Hao H Cao Lei L Zhang Huan H Zhong Zhaoshan Z Zhou Li L Lian Chao C Wang Xiaocheng X Chen Hao H Wang Minxiao M Zhang Xin X Li Chaolun C

PLoS biology 20250826 8

The alvinellid worm Paralvinella hessleri is the only animal that colonizes the hottest part of deep-sea hydrothermal vents in the west pacific. We found P. hessleri accumulates exceptionally high level of toxic element arsenic (>1% of wet weight) and tolerated elevated concentrations hydrogen sulphide. Using advanced microscopy, elementary analysis, and genomics and proteomics approaches, we identified a previously unrecognized arsenic-sulfide biomineralization process in P. hessleri. Our data ...[more]

PMID: 40857221

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