Proteomics

Dataset Information

0

SILAC experiment quantifying the proteomics of WT and HBO1-KO HeLa


ABSTRACT: Lysine lactylation (Kla) links metabolism and gene regulation and plays a key role in multiple biological processes. We report that HBO1 functions as a lysine lactyltransferase to regulate transcription. Quantitative proteomic analysis further revealsed 95 endogenous Kla sites targeted by HBO1, with the majority located on histones.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Cervix Squamous Epithelium

DISEASE(S): Cervix Carcinoma

SUBMITTER: siyu wang  

LAB HEAD: Kai Zhang

PROVIDER: PXD051415 | Pride | 2024-04-13

REPOSITORIES: Pride

Similar Datasets

2023-08-24 | PXD037027 | Pride
2024-05-09 | PXD050906 | Pride
2022-08-11 | PXD033991 | Pride
2024-01-16 | GSE239656 | GEO
2024-01-26 | PXD046488 | Pride
2022-06-30 | GSE171088 | GEO
2024-04-07 | PXD022700 | Pride
2022-06-30 | GSE171832 | GEO
2022-06-09 | PXD031526 | Pride
2022-10-15 | PXD032921 | Pride