4D label free phosphorylation modification omics of 60 human esophageal cancer tissue samples
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: 
Li ShuJun
LAB HEAD: Bin Li
PROVIDER: PXD051858 | Pride | 2026-06-29
REPOSITORIES: Pride
Dataset's files
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|---|---|---|---|---|
| YD209LPST.rar | Other | |||
| txt.zip | Other |
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Publications
2-Hydroxyisobutyrylation and Phosphorylation Crosstalk Guides Metastasis Prediction and Immunotherapy in Esophageal Squamous Cell Carcinoma.
Li Junyi J Li Shujun S Yu Xiaomei X Mu Qier Q Luo Maowen M Wang Yuzhen Y Liu Zhichao Z Gu Chengwei C Chen Jiaxi J He Wangcheng W Yang Tong T He Yan Y Pei Xiaoya X Lin Mao M Li Zhigang Z Liu Jun J Zhao Baosheng B Zhang Fan F Liu Jinbao J Li Bin B Xu Wenwen W
MedComm 20260619 7
Posttranslational modification (PTM) is pivotal in cancer progression. However, the mechanisms, biological function, and clinical significance underlying PTM crosstalk are unclear. Here, we performed systematic analyses of 2-hydroxyisobutyrylation (Khib), phosphoproteomic, proteomic, and transcriptomic profiles from 60 esophageal squamous cell carcinoma (ESCC) samples, comprising matched normal, primary tumor, and metastatic lymph node tissues. The integrative analysis identified 4499 proteins c ...[more]
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