CAD-binding protein identification in HepG2 cells

ABSTRACT: To probe the possible mechanism by which CAD (trifunctional carbamoyl-phosphate synthase, aspartate transcarbamoylase, and dihydroorotase) promotescancer cell proliferation, we purified CAD via affinity chromatography from HepG2 cells stably expressing CAD-FLAG and identified its interacting proteins by tandem mass spectrometry.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hepatocyte, Cell Culture

DISEASE(S): Adult Hepatocellular Carcinoma

SUBMITTER: Chao Qin  

LAB HEAD: Pinghui Feng

PROVIDER: PXD052153 | Pride | 2026-02-03

REPOSITORIES: Pride