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Shotgun proteomics experiments to identify covalent modification of proteins in HCT116 cells by a novel covalent ligand, CL16

ABSTRACT: By coupling activity-based protein profiling (ABPP) with covalent ligand screening experiment, we have identified a cysteine-reactive covalent ligand, CL16, which can bind strongly and selectively with RhoA in vitro. In this experiment, we performed shotgun proteomics to investigate protein targets of CL16 in colorectal cancer HCT116 cells.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Clive Yik-Sham CHUNG

LAB HEAD: Clive Yik-Sham Chung

PROVIDER: PXD053036 | Pride | 2025-08-30

REPOSITORIES: Pride

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			Action	DRS
	20221010_HCT25_Slot1-32_1_9980.d.zip	Other
	20221010_HCT50_Slot1-33_1_9986.d.zip	Other
	Result.zip	Other
	checksum.txt	Txt
	mqpar.xml	Xml

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