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MiR-493-5p, miR-3662, miR-589-3p, human A549 cells, LC-MSMS

ABSTRACT: miR-493-5p, miR-3662, and miR-589-3p were estimated as working microRNAs in bleomycin- and methotrexate-induced phenotypic changes in A549 cells via microRNAs-Proteins Analysis of Integrative Relationship (miR-PAIR). To verify the effect of these miRNAs on the their target protein expression levels, comprehensive expression of proteins in A549 cells treated with miR-493-59, miR-3662, and miR-589-3p mimic was examined by SWATH-MS method. As expected by a miR-PAIR mehtod, almost target proteins were succesfully regulated by miR-493-5p and miR-589-3p mimics.

INSTRUMENT(S): ZenoTOF 7600

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung, Epithelial Cell

DISEASE(S): Pulmonary Fibrosis

SUBMITTER: Masashi Kawami

LAB HEAD: Yasuo Uchida

PROVIDER: PXD053397 | Pride | 2025-07-25

REPOSITORIES: Pride

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			Action	DRS
	20240131_akai_A549_BLM_60uguL_500ng_ZenoSW_n1.wiff	Wiff
	20240131_akai_A549_BLM_60uguL_500ng_ZenoSW_n1.wiff.dia	Wiff
	20240131_akai_A549_BLM_60uguL_500ng_ZenoSW_n1.wiff.dia.quant	Wiff
	20240131_akai_A549_BLM_60uguL_500ng_ZenoSW_n1.wiff.scan	Wiff
	20240131_akai_A549_BLM_60uguL_500ng_ZenoSW_n1.wiff2	Wiff

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