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Proteome of ESCC identified by LC-MS/MS

ABSTRACT: Protein identification in esophageal squamous cell carcinoma(ESCC) was performed,we explored the proteomic landscape in ESCC and attempted to perform clinical-related patient classification based on ESCC proteome.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Xiaoyi Yuan

LAB HEAD: Xiaoyi Yuan

PROVIDER: PXD053809 | Pride | 2026-06-15

REPOSITORIES: Pride

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			Action	DRS
	N_238_20221127.raw	Raw
	N_239_20221120.raw	Raw
	N_240_20221123.raw	Raw
	N_242_20221120.raw	Raw
	N_243_20221120.raw	Raw

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Publications

Proteomics analysis and immune profiling reveal regulators of PD-L1 in oesophageal squamous cell carcinoma.

Li Yuying Y Yuan Xiaoyi X Yin Xing-Feng XF Zheng Dandan D Shi Fujin F Liu Danya D Hu Liling L Shi Xinyu X Wen Nengqiao N He Qing-Yu QY Yang Hong H Zhang Chris Zhiyi CZ

British journal of cancer 20250610 4

<h4>Background</h4>Proteomics studies have advanced our comprehension of cancer biology, accelerated targeted therapy, and improved patient outcomes.<h4>Methods</h4>High-resolution mass spectrometry and immune profiling based on immunohistochemistry and multiple immunohistochemistry were employed to investigate proteomic and immune landscapes in oesophageal squamous cell carcinoma (ESCC) and explore the regulators of PD-L1 in ESCC. Molecular validation was performed using qRT-PCR, western blotti ...[more]

PMID: 40490504

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Gene expression in normal and tumoral esophageal squamous cell lines

Project description:This study was designed to identify genes aberrantly expressed in esophageal squamous cell carcinoma (ESCC) cells. Three esophageal squamous cell carcinoma-derived cell lines and one normal human esophageal squamous cell line were analyzed.

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Microarray expression profile and functional analysis of circular RNAs in plasma for Esophageal Squamous Cell Carcinoma

Project description:The purpose of this study is to explore the circRNAs expression profiles in the plasma from esophageal squamous cell carcinoma (ESCC) patients.The purpose of this study is to explore the circRNAs expression profiles in the plasma from esophageal squamous cell carcinoma (ESCC) patients.

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Squamous esophagus

Project description:SAGE libraries made of squamous esophagus tissue, primary cell culture or esophageal squamous cell carcinoma Keywords: SAGE analysis of different tissues squamous esophagus biopsy was taken from 1 male metaplastic Barrett's esophagus patient. primary cell culture was from 1 male Barrett's esophagus patient. Esophageal squamous cell carcinoma was from a patient known to have ESCC

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Human esophageal dysplasia (16 cases) vs. esophageal squamous cell carcinoma (59 cases)

Project description:Our aim is to identify frequent genomic aberrations both in ESCC and esophageal dysplasia, and to discover important copy number-driving genes and microRNAs in ESCC. We carried out array-based comparative genomic hybridization (array CGH) on 59 ESCC resection samples and 16 dysplasia biopsy samples. Expression of genes at 11q13.3 was analyzed by real-time PCR and immunohistochemistry (IHC). Integrated analysis was performed to identify genes or microRNAs with copy number-expression correlations. Two group experiment, esophageal dysplasia vs. esophageal squamous cell carcinoma. Biological replicates: 16 dysplasias vs. 59 carcinomas

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