Pyroptosis therapy targeting TNBC

ABSTRACT: Biomimetic nanococrystals are prepared using the preferred combination of mitoxantrone and gambogic acid for rational drug delivery. The unique mechanism of obtained nanococrystals regulating pyroptosis genes through ribosomal stress is revealed by TMT-proteomics of 4T1 cells.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Malignant Cell, Cell Culture

DISEASE(S): Breast Cancer

SUBMITTER: Boshu Ouyang  

LAB HEAD: Zhiqing Pang

PROVIDER: PXD053939 | Pride | 2024-07-27

REPOSITORIES: Pride