Dataset Information

Proteomics-Based Pilot Study on Heatstroke Recovery and Organ Injury Risk Assessment: Analysis of Clinical Human Heatstroke Cases Using Plasma Samples from Mild Heatstroke Conditions

ABSTRACT: This project focuses on identifying biomarkers in non-invasive samples from clinical cases to monitor heatstroke and diagnose it early. The approach utilizes a top-down proteomics strategy applied to patient plasma samples collected at two critical time points: diagnosis and recovery. This method aims to enhance understanding and detection capabilities for better management of heatstroke.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

SUBMITTER: Jiayi Jin

LAB HEAD: Jiayi Jin

PROVIDER: PXD054006 | Pride | 2026-02-09

REPOSITORIES: Pride

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Publications

Proteomics-based monitoring of heatstroke recovery identifies molecular signatures of organ stress.

Jin Jiayi J Wong Sing Ying SY Kondo Kenta K Iba Toshiaki T Hayashi Nobuhiro N

Communications medicine 20250901 1

<h4>Background</h4>Global warming exacerbates heatstroke, increasing its severity and associated health risks, including fatal kidney damage. Predicting post-heatstroke organ injury remains difficult, delaying timely medical intervention. This study aims to identify potential blood biomarkers that reflect organ stress and recovery status following heatstroke.<h4>Methods</h4>Plasma samples (n = 12) from clinically diagnosed classical (non-exertional) heatstroke patients were collected at diagnosi ...[more]

PMID: 40890430

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			Action	DRS
	HP_109.mgf	Mgf
	HP_109.msf	Msf
	HP_109.mzid.gz	Mzid
	HP_183.mgf	Mgf
	HP_183.msf	Msf