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Proteomic analysis of purified neutrophils

ABSTRACT: We analyzed the whole proteome of purified neutrophils using a label free proteomic bootom up approach.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Neutrophil, Blood

SUBMITTER: Emilie-Fleur GAUTIER

LAB HEAD: Dr Slim Azouzi

PROVIDER: PXD054067 | Pride | 2025-07-23

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	ClVK201125_SSHU_031220_O_prot_SCX1_A39306_RN20_1_1567.d.7z	Other
	ClVK201125_SSHU_031220_O_prot_SCX2_A39307_RN21_1_1568.d.7z	Other
	ClVK201125_SSHU_031220_O_prot_SCX3_A39308_RN22_1_1569.d.7z	Other
	ClVK201125_SSHU_031220_O_prot_SCX4_A39309_RN23_1_1570.d.7z	Other
	ClVK201125_SSHU_031220_O_prot_SCX5_A39310_RN24_1_1571.d.7z	Other

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Publications

The neutrophil antigen 3a/b polymorphism in SLC44A2 unexpectedly encodes the Csa/Csb red cell antigens.

Duval Romain R Soudry Alissa A De Oliveira Rios Jonathan J Linguet Sarah Liane SL Taillepierre Miguel M Matesic Graziella G Raneri Alexandre A Laiguillon Guy G Le Toriellec Emilie E Gautier Emilie-Fleur EF Vainqueur Damien D Babinet Jérôme J Masson Cécile C Gelly Jean Christophe JC Le Van Kim Caroline C Romana Marc M Chen Dawei D Santoso Sentot S Koehl Berengere B Peyrard Thierry T Azouzi Slim S

Blood 20250701 2

<h4>Abstract</h4>The Csa blood group antigen was identified >50 years ago, but its genetic basis has yet to be elucidated. All our recent genomic investigation has failed to resolve the genetic basis of this enigmatic antigen. By investigating the association of the human neutrophil antigen (HNA)-3a/b polymorphism (rs2288904-G/A) in SLC44A2 with clinical features of sickle cell disease, we incidentally discovered that rare subjects with the homozygous HNA-3b/b genotype also carry the uncommon Cs ...[more]

PMID: 40090003

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