Data-independent acquisition proteomics enhances cellular nucleic acid binding protein characterization in colitis data2

ABSTRACT: We developed a robust workflow for in-depth analysis of NABPs, which combining immobilized metal affinity chromatography capture and data-independent acquisition. This workflow enhances the identification and quantification of NABPs. We then applied this workflow to colitis mouse and discovered epigenetic processes, particularly histone methylation was significantly changed in spleen.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Spleen

SUBMITTER: Huiyu Wang  

LAB HEAD: Hua Xiao

PROVIDER: PXD054774 | Pride | 2025-12-01

REPOSITORIES: Pride