Combination of Metabolomics, Lipidomics and Molecular Biology to Investigation of Metabolic Disturbance of Short-Term Administration of Emodin

ABSTRACT: To comprehensively elucidate the possible mechanism of short-term administration of emodin on the metabolic disturbance in vivo, our study utilized both LC/MS and NMR platforms for untargeted metabolomics studies. These analyses aimed to identify potential biomarkers associated with emodin-induced metabolic disturbances in mice. Subsequently, we delved into lipidomics to explore lipid metabolism systematically and determined the position of C=C double bonds in unsaturated lipids.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Blood Plasma, Liver

SUBMITTER: Haitao Wang  

LAB HEAD: Lifeng Han

PROVIDER: PXD055000 | Pride | 2024-10-17

REPOSITORIES: Pride