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DIA proteomics analysis of FGF2-treated human retinal microvascular endothelial cells

ABSTRACT: Human retinal microvascular endothelial cells were stimunlated with 0 or 50 ng/ml FGF2 and then applied for DIA proteomics.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture, Microvascular Endothelial Cell

SUBMITTER: Dan Liao

LAB HEAD: Dan Liao

PROVIDER: PXD055191 | Pride | 2025-05-07

REPOSITORIES: Pride

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	CN-1.raw	Raw
	CN-2.raw	Raw
	CN-3.raw	Raw
	EXP-1.raw	Raw
	EXP-2.raw	Raw

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Publications

ENO2-Regulated Glycolysis in Endothelial Cells Contributes to FGF2-Induced Retinal Neovascularization.

Liao Dan D Wang Jie J Zhang Xiaoyu X Li Rong R Yang Xiaoli X

Investigative ophthalmology & visual science 20250101 1

<h4>Purpose</h4>Ocular neovascularization is a major cause of blindness. Although fibroblast growth factor-2 (FGF2) has been implicated in the pathophysiology of angiogenesis, the underlying mechanisms remain incompletely understood. The purpose of this study was to investigate the role of FGF2 in retinal neovascularization and elucidate its underlying mechanisms.<h4>Methods</h4>The oxygen-induced retinopathy mouse model was used to study the pathogenesis of retinal neovascularization. Immunoflu ...[more]

PMID: 39854009

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