Proteomics

Dataset Information

C-terminal amides mark proteins for degradation via SCF/FBXO31

ABSTRACT: FBXO31 is a substrate adapter for the SCF-type ubiquitin ligase complex SCF/FBXO31 which ubiquitylates C-terminal amide-bearing proteins (CTAPs), thereby triggering their proteasomal degradation in human cells. Profiling of active cullin-RING ubiquitin E3 ligases was performed in naive or FBXO31 knockdown cell lines treated with hydrogen peroxide.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Mario Oroshi  

LAB HEAD: Matthias Mann

PROVIDER: PXD055518 | Pride | 2024-11-07

REPOSITORIES: Pride

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CRL_profiling_pg_matrix.tsv Tabular
CRL_profiling_raw_files.zip Other
PXD055518_community_annotated.sdrf.tsv Tabular
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