Dataset Information
Proteomic approaches using UHPLC-MS/MS in serum from Trypanosoma cruzi-infected mice
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Blood Serum
DISEASE(S): Chagas Disease
SUBMITTER: 
Eloan Mendes Vieira
LAB HEAD: Cláudia Martins Carneiro
PROVIDER: PXD056503 | Pride | 2026-04-06
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| Be78_NT20_Acute_R1.raw | Raw | |||
| Be78_NT20_Acute_R2.raw | Raw | |||
| Be78_NT20_Acute_R3.raw | Raw | |||
| Be78_NT20_chronic_R1.raw | Raw | |||
| Be78_NT20_chronic_R2.raw | Raw |
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Publications
Serum Proteomics Provides Novel Biomarkers of Inflammation, Tissue Injury, and Therapeutic Response in Experimental Chagas Disease.
Microorganisms 20260305 3
Chagas disease remains a major public health challenge and still lacks reliable serum biomarkers capable of accurately reflecting disease progression and therapeutic response. Here, we performed a quantitative label-free serum proteomic analysis in a murine model infected with two <i>Trypanosoma cruzi</i> strains exhibiting contrasting sensitivity to benznidazole (Be-78, sensitive; VL-10, resistant), evaluated during both acute and chronic phases, in the presence or absence of treatment. Distinc ...[more]
