Anaerobic synthetic microbial communities

ABSTRACT: Anaerobic microbial communities play a critical role in biogeochemical cycles through complex networks of interactions that influence community structure, stability, and functionality. This study investigates the metabolic interactions within synthetic communities composed of a cellulolytic bacterium (Ruminiclostridium cellulolyticum), a hydrogenotrophic methanogen (Methanospirillum hungatei), an acetoclastic methanogen (Methanosaeta concilii), and a sulfate-reducing bacterium (Desulfovibrio vulgaris). Through proteogenomic analysis and metabolic modeling, we quantified the metabolic interaction potential and metabolic resource overlap across bi-, tri-, and quad-cultures.

INSTRUMENT(S):

ORGANISM(S): Desulfovibrio Vulgaris Str. Hildenborough Methanospirillum Hungatei Jf-1 Clostridium Cellulolyticum (strain Atcc 35319 / Dsm 5812 / Jcm 6584 / H10) Methanothrix Soehngenii Gp6

TISSUE(S): Cell Culture

SUBMITTER: Dongyu Wang  

LAB HEAD: Chongle Pan

PROVIDER: PXD056517 | Pride | 2025-09-22

REPOSITORIES: Pride