Proteomics

Dataset Information

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Proteomic response of Escherichia coli to polyionene 6,6

ABSTRACT: This project contributes to the proteomic comparison of the dynamics of Escherichia coli O107 grown in TSB without polyionene 6,6 (PI 6,6) and with PI 6,6 either at 0.5 x Minimum Inhibitory Concentration (MIC) or 0.75 x MIC.

INSTRUMENT(S):

ORGANISM(S): Escherichia Coli O107

SUBMITTER: Jean ARMENGAUD  

LAB HEAD: Jean Armengaud

PROVIDER: PXD056732 | Pride | 2025-09-15

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
EcoliO107_NCBI_20221201.fasta Fasta
F227948.dat Other
F227948_p0.01.mzid.gz Mzid
F227949.dat Other
F227949_p0.01.mzid.gz Mzid
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Publications

Proteomics reveals the key molecular players in Escherichia coli exposed to the antimicrobial cationic polymer 6-6 polyionene.

Pistol A A   Armengaud J J   Carrot G G   Tortech L L   Alpha-Bazin B B  

Journal of hazardous materials 20250819

Polyionenes are polymers with antibacterial properties that hold great promise for the development of applications aiming to preserve against microbial surface contamination. In this study, the effect of 6-6 polyionene (PI 6-6) on a model Gram-negative bacterium, Escherichia coli, was deciphered using next-generation, label-free shotgun proteomics. Cells were exposed to two sub-minimum inhibitory concentrations (MIC) of the polymer before performing comprehensive proteomic analysis. Under these  ...[more]

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