Human MS Lesions ABPP - foamy microglia link oxylipins to disease progression in multiple sclerosis

ABSTRACT: In this study lesions from human MS brains and controls were isolated and analyzed by Activity-based protein profiling using fluorophosphonate- and beta-lacton probes to enrich active enzymes from the samples. these were subsequently analyzed by LC/MS-MS.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

DISEASE(S): Secondary Progressive Multiple Sclerosis

SUBMITTER: Daan Van der Vliet  

LAB HEAD: Mario van der Stelt

PROVIDER: PXD056899 | Pride | 2026-09-07

REPOSITORIES: Pride