Global proteomics profiling of Huh7 cells infected with human coronaviruses (SARS-CoV-2, HCoV-229E, and HCoV-OC43)
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ABSTRACT: To explore host factors and pathways modulated by coronavirus infections, we performed global quantitative proteomics profiling. Huh7 cells were infected with SARS-CoV-2 (MOI=1.0), HCoV-229E (MOI=0.1), or HCoV-OC43 (MOI=1.0) for 24 hours, compared with MOCK infection. Protein samples were digested and analyzed using mass spectrometry with a data-independent acquisition (DIA) approach to measure changes in global protein abundance. This study complements the phosphoproteomics dataset (PXD057224) from the same study
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
SUBMITTER:
Kuai Yu
LAB HEAD: Kuai Yu
PROVIDER: PXD057194 | Pride | 2026-04-01
REPOSITORIES: Pride
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