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Human cancer YD15 Fadu con ITGA4 LC-MS

ABSTRACT: The effects of ITGA4 on OSCC(YD15, Fadu) were investigated by cell-based assays, proteome analysis,

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Se-Ho Jeong

LAB HEAD: Sang-Gun AHN

PROVIDER: PXD057268 | Pride | 2026-06-08

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	JSU-JSH.msf	Msf
	JSU-JSH.pdResult	Other
	JSU-JSH.pdStudy	Other
	JSU-JSH_FaduControl.raw	Raw
	JSU-JSH_FaduITGA4.raw	Raw

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Publications

Hypermethylation‑induced silencing of ITGA4 promotes oral squamous cell carcinoma progression through SNX5 upregulation.

Tien Nguyen Ngoc Thuy NNT Choe Han-Cheol HC Ahn Sang-Gun SG

Oncology reports 20260424 6

Epigenetic modifications, especially DNA methylation, play an increasingly important role in oral cancer. However, their specific contributions to the progression of oral squamous cell carcinoma (OSCC) remain unclear. The present study used the Shiny Methylation Analysis Resource Tool (SMART) database (https://smart.embl.de/smart/change_mode.cgi) to identify methylation‑driven genes associated with OSCC. Among the identified candidates, integrin subunit α4 (ITGA4) exhibited significantly elevate ...[more]

PMID: 42028750

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