Proteomics

Dataset Information

0

Acetylome analysis of HepG2 cells after treatment with PBS or LukS-PV


ABSTRACT: We previously reported that LukS-PV, a component of Panton-Valentine interleukin (PVL), has anti-leukaemic activity, inducing differentiation, increasing apoptosis and inhibiting proliferation of acute myeloid leukaemia (AML) cells. In addition, our study showed that LukS-PV could inhibit the progression of hepatocellular carcinoma (HCC) by targeting C5aR. To investigate the biological mechanisms involved, we performed acetylome analysis on PBS/LukS-PV-treated HCC cells to search for important downstream regulators.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

DISEASE(S): Liver Cancer

SUBMITTER: Xiaoling Ma  

LAB HEAD: Xiaoling Ma

PROVIDER: PXD057287 | Pride | 2026-01-02

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
1-Basic_analysis.zip Other
2-Differentially_expressed_protein.zip Other
3-Protein_annotation.zip Other
4-Functional_classification.zip Other
5-Functional_enrichment.zip Other
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