Dataset Information

PROTEOMIC PROFILING OF EXTRACELLULAR VESICLES IN INFLAMMATORY BOWEL DISEASES

ABSTRACT: Differentially expressed proteins have been identified in EVs from patients with CD and UC, depending on the presence of disease, the disease type, and the disease activity. These proteins may hold potential as biomarkers and open new avenues for research into the understanding of these conditions.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Colon

SUBMITTER: Ibon Iloro

LAB HEAD: Montse Baldán-Martín

PROVIDER: PXD057391 | Pride | 2025-05-07

REPOSITORIES: Pride

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Publications

Proteomic Profiling of Extracellular Vesicles in Inflammatory Bowel Diseases.

Baldán-Martín Montse M Azkargorta Mikel M Lapitz Ainhoa A Ortega Moreno Lorena L Iloro Ibon I Fernández-Tomé Samuel S Arbelaiz Ander A Escobes Iraide I Marín Alicia C AC Bernardo David D Bujanda Luis L Bañales Jesús M JM Elortza Felix F Gisbert Javier P JP Chaparro María M

International journal of molecular sciences 20250109 2

The proteomic analysis of serum extracellular vesicles (EVs) could be a useful tool for studying the pathophysiology of Crohn's disease (CD) and ulcerative colitis (UC), as well as for biomarker discovery. To characterize the proteomic composition of serum EVs in patients with CD and UC to identify biomarkers and molecular pathways associated with pathogenesis and activity. Methods: Serum EVs were enriched and analyzed in patients with quiescent CD, active CD (aCD), quiescent UC, active UC (aUC) ...[more]

PMID: 39859242

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	101_HC24_Set5.raw	Raw
	102_UC_Act20_Set5.raw	Raw
	103_UC_Act21_set5.raw	Raw
	104_UC_Act22_Set5.raw	Raw