Lon Protease-Mediated Secretome Profiling in Klebsiella pneumoniae

ABSTRACT: Lon protease is a global regulator in bacteria, affecting biofilm formation, antibiotic resistance, toxin-antitoxin complexes and proteolysis of damaged proteins. This study uses bottom-up proteomics to identify Klebsiella pneumoniae proteins with altered secretion patterns in the absence of lon and provide insight into Lon mediation of the extracellular environment.

INSTRUMENT(S):

ORGANISM(S): Klebsiella Pneumoniae

TISSUE(S): Cell Suspension Culture

SUBMITTER: Chelsea Reitzel  

LAB HEAD: Jennifer Geddes-McAlister

PROVIDER: PXD057415 | Pride | 2024-11-01

REPOSITORIES: Pride