Mettl1-mediated B cell responses

ABSTRACT: Germinal center (GC) response requires increased protein synthesis. We identify the methyltransferase METTL1 as a translational checkpoint during GC responses. Therefore, we immunized mettl1-cko mice and control mice with NP-OVA, and sorted spleen B cells on day 14.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Spleen

SUBMITTER: Shuyi Wang  

LAB HEAD: Hui Zhang

PROVIDER: PXD057426 | Pride | 2024-11-01

REPOSITORIES: Pride