Dataset Information
Human blood LC-MSMS Simple Protein Identification Report
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Blood Cell, Blood
DISEASE(S): Multiple Myeloma
SUBMITTER: 
GUO XIN
LAB HEAD: Ye Yang
PROVIDER: PXD057487 | Pride | 2025-05-13
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| ARP1-USP13-OE.raw | Raw | |||
| ARP1-WT.raw | Raw | |||
| checksum.txt | Txt | |||
| peptides.txt | Txt | |||
| proteinGroups.txt | Txt |
Items per page: 1 - 5 of 5 |
Publications
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma.
Basic & clinical pharmacology & toxicology 20250401 5
Multiple myeloma (MM) is an incurable hematologic malignancy, driving significant interest in the discovery of novel therapeutic strategies. Bruceine A (BA), a tetracyclic triterpene quassinoid derived from Brucea javanica, has shown anticancer properties by modulating multiple intracellular signalling pathways and exhibiting various biological effects. However, the specific pharmacological mechanisms by which it combats MM remain unclear. In this study, we identified USP13 as a potential target ...[more]
