Proteomics

Dataset Information

0

Identification of substrates of ZDHHC19 in mouse haploid spermatids using Acyl RAC


ABSTRACT: Reversible palmitoylation is catalyzed by palmitoyltransferase(PAT) from the zinc-finger DHHC domain-containing protein (ZDHHC) family. The Zdhhc19 knockout male mice showed infertility and Zdhhc19 deficient sperm showed severe morphological defects. To identify the candidate substrates of ZDHHC19 in haploid spermatids, we carried out label free mass spectrometry (MS) combined with resin-assisted capture (RAC) methods. This study reveals the role of palmitoylation mediated by ZDHHC19 during spermiogenesis.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Testis

SUBMITTER: Jiaoyang Li  

LAB HEAD: Ruibao Ren

PROVIDER: PXD057735 | Pride | 2025-09-10

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
KO-CBF1.raw Raw
KO-CBF2.raw Raw
KO-PBF1.raw Raw
KO-PBF2.raw Raw
WO-PBF2.raw Raw
Items per page:
1 - 5 of 11

Similar Datasets

2025-09-10 | PXD057727 | Pride
2025-09-15 | PXD060045 | Pride
2021-06-23 | PXD025286 | Pride
2017-09-29 | PXD003039 | Pride
2018-10-18 | PXD010326 | Pride
2023-10-04 | PXD041525 | Pride
2024-12-17 | GSE235254 | GEO
2024-12-17 | GSE235258 | GEO
2019-07-16 | PXD012736 | Pride
2024-02-04 | GSE169248 | GEO