Identification of PRRC2B methylation sites
Ontology highlight
ABSTRACT: It was hypothesized that the human PRRC2B protein (Uniprot accession Q5JSZ5) interacts with its RNA binding targets via methylated arginines. The protein contains at least two RG rich motifs (residues 1061-1080, and 1104-1124), in which the arginines are hypothesized to be methylated. The goal of the experiment was to identify such methylated PRRC2B arginines. To get a wide coverage of the RG rich domains, an immuno-precipitation experiment was performed, followed by digestion with chymotrypsin and LC-MS/MS analysis.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER:
Alon Savidor
LAB HEAD: Prof. Adi
PROVIDER: PXD057790 | Pride | 2025-10-26
REPOSITORIES: Pride
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