Identification of CASK nuclear interactome in resting and H5N1-activated GM-macrophage by IP-LC-MS/MS

ABSTRACT: We investigated how nuclear CASK regulates the export of Ifna mRNA to the cytosol. As CASK is a scaffold protein known to interact with many proteins via its PDZ, L27, SH3, and GK domain, we explored whether CASK interacts with nuclear proteins involved in the export of messenger ribonucleoprotein (mRNP) to the cytosol.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Bone Marrow, Macrophage

DISEASE(S): Avian Influenza

SUBMITTER: Jing-Ying Huang  

LAB HEAD: Shie-Liang Hsieh

PROVIDER: PXD058016 | Pride | 2025-01-09

REPOSITORIES: Pride