MFGE8 induces anti-PD-1-therapy resistance by promoting extracellular vesicle sorting of PD-L1

ABSTRACT: To elucidate which secreted factors in tumor tissues (TTs) are responsible for the upregulation of UBE4A as the tumor progresses, we inoculated tumors in mice and analyzed the 2- and 4-week TT fluid by mass spectrometry (MS). By combining molecular weight cut off(MWCO) and the identification of secreted proteins, we identified three candidate proteins.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: peihan wu  

LAB HEAD: Zhijian Cai

PROVIDER: PXD058079 | Pride | 2025-05-07

REPOSITORIES: Pride