Chronic inflammation drives epididymal tertiary lymphoid structure formation and autoimmune fertility disorders
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ABSTRACT: We characterized the sperm proteins recognized by the antibodies in mouse serum and epididymal fluid after immune tolerance disruption by performing mass spectrometry-based label-free quantitative proteomics. For this, we immunoprecipitated sperm cell protein extractions with serum and epididymal fluids from the proximal and distal epididymis of WT and Foxp3-DTR transgenic mice 2 weeks after Treg depletion.
INSTRUMENT(S):
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Sperm
SUBMITTER:
Maia Elizagaray
LAB HEAD: Maria Agustina Battistone
PROVIDER: PXD058247 | Pride | 2025-07-10
REPOSITORIES: Pride
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