HDX-MS Studies of Dengue Virus Serotype 2 NS5 (DENV2 NS5) and Stem Loop A (SLA) Interactions

ABSTRACT: The project employs HDX-MS to study the conformational dynamics of DENV2 NS5 in its apo form and in complex with the viral promoter RNA, Stem Loop A (SLA). The conformational dynamics of the RdRp domain of DENV2 NS5 (NS5-RdRp) in its apo form and in complex with SLA was also studied.

INSTRUMENT(S):

ORGANISM(S): Escherichia Coli

SUBMITTER: Juliet Obi  

LAB HEAD: Daniel J. Deredge

PROVIDER: PXD058297 | Pride | 2025-05-07

REPOSITORIES: pride