In vivo identification of Toxoplasma gondii antigenic proteins and in silico study of their polymorphism.
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ABSTRACT: This study aims to identify novel candidates for the development of serotyping assays for Toxoplasma gondii (T. gondii). We employed an in vivo approach, utilizing co-immunoprecipitation (Co-IP) with sera from infected mice to identify antigenic proteins, followed by detection via LC-MS/MS. Additionally, an in silico analysis was conducted to explore the genetic polymorphism of the genes encoding these proteins and to determine mutations associated with specific genotypes.
INSTRUMENT(S):
ORGANISM(S): Toxoplasma Gondii
TISSUE(S): Tachyzoite
SUBMITTER:
Hélène Diemer
LAB HEAD: Sarah Cianferani
PROVIDER: PXD058695 | Pride | 2026-02-09
REPOSITORIES: Pride
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